- A Study on Serum Zinc Concentration in some Methamphetamine Abusers.
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Hyung Il Moon, Hoo Rak Lee, Soo Il Lee
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Korean J Prev Med. 1992;25(2):172-179.
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 Abstract
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- The author investigated the zinc concentrations in sera of 110 methamphetaimine abusers (male 87, female 23) and of 41 healthy official workers(male 29, female 12) using inductively coupled plasma emission spectrometer. The serum zinc concentrations were analysed according to hepatitis C virus antibody(Anti HCV), hepatitis B surface antigen(HBsAg) and alanine aminotransferase (ALT) value in both groups. The analytical results were obtained as follows; 1. The mean zinc concentration of MAP abuser group(298.5+/-246.9 microgram/100 microliter) was 2.5 times higher than that of control group(118.8+/-25.4 microgram/100 microliter). 2. The distribution of zinc concentration in both groups were skewed pattern. 3. The zinc concentration were higher in Anti HCV-positive group and abnormal ALT value group than Anti HCV-negative group and normal ALT value group. But HBs-Ag positive group had lower zinc concentration than HBs-Ag negative group. 4. The number of anti HCV-positive subjects was increased and the zinc concentration were decreased in proportion to the abusing duration of MAP.
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Summary
- Seroprevalence of antibody to the hepatitis C virus in methamphetamine abusers.
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Jin Kyoo Kim, Ji Ho Lee, Byung Mann Cho, Soo Il Lee
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Korean J Prev Med. 1991;24(4):465-472.
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Abstract
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- This study was designed to estimate the prevalence of hepatitis C virus(HCV) infection in drug abusers. The subjects were 141 inpatients who had been admitted to a general hospital with the symptoms and signs of methamphetamine intoxication. Seroprevalence of antibody to the hepatitis C virus(anti-HCV) was 60.3%,(85/141) and it was higher in the group with increased frequency and duration of drug abuse, but such a relationship was not found in the seroprevalence of hepatitis B surface antigen(HBsAg). These findings suggested the possibility of high prevalence of HCV infection in methamphetamine abusers, and the importance of repetitive percutaneous injection in the transmission of HCV infection.
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Summary
- A Study on the Urinary Lead Excretion after Oral D-penicillamine Administration.
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Soo Il Lee
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Korean J Prev Med. 1979;12(1):43-48.
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Abstract
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- For the purpose of further health control, D-penicillamine was orally administered to 8 persons who were employed in lead industry and suspected lead intoxication routine industrial health examination. The dose of D-penicillamine was 600 mg per day and was administered orally in every other 5 days. For the laboratory analyses 24 hours urine and 10 gm of whole blood were collected every day. The results were as follows ; 1. It was found that mean urinary lead excretion per day was 446.5 g/l and 394.98 g/l, respectively during the first 5-day and the second 5-day administration with D-penicillamine. 2. Mean lead excretion per day was 130.56 +/- 66.42 g/l after first 5-day administration and 159.28 +/- 104.44 g/l after second 5-day administration with D-penicillamine. 3. The level of urinary lead excretion after administration increased 3 to 4 times than that before administration with D-penicillamine. 4. Blood and urinary lead level investigate after 6 months were 44.4 +/- 10.2 g/100g and 72.7 +/- 29.7 g/l for the eight persons.
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Summary
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